What Are the Signs of Hormonal Imbalance in Women?

The signs that your hormones need support include persistent fatigue, irregular or painful periods, bloating, mood instability, hormonal acne, unexplained weight changes, and a general sense that your body is working against you despite doing everything right. But before we go further, I want to address something, because the phrase "hormonal imbalance" is one I use reluctantly.

Recognising yourself in any of this? The free Hormone Health Checklist is a useful starting point.

Why "hormonal imbalance" isn't quite the right phrase

Hormones don't balance. That's not how they work. They fluctuate constantly across your day, across your cycle, across your life, and those fluctuations are not a problem to be fixed. They are your physiology doing exactly what it's supposed to do.

What we actually mean when we say "hormonal imbalance" is that something in the body is producing, metabolising, or responding to hormones in a way that's creating symptoms. It might be that oestrogen is being reabsorbed rather than eliminated because the gut microbiome is imbalanced. It might be that progesterone production is low because chronic stress is stealing the precursor it needs. It might be that blood sugar dysregulation is keeping cortisol elevated in a way that disrupts everything else downstream.

These are specific, identifiable, addressable things. Not a vague imbalance that needs balancing.

I use the term because it's the language most women use when they're searching for answers. But I want to be clear that the goal of my work is never to "balance your hormones." It's to understand what's driving your symptoms and address that.

With that said, here are the signs worth paying attention to.

Fatigue that sleep doesn't fix

This is one of the most universal and most dismissed hormonal symptoms. Not tiredness at the end of a long day. Genuine, persistent fatigue that's there when you wake up and doesn't lift regardless of how much sleep you get.

Several hormonal patterns contribute to this. Low thyroid function, disrupted adrenal output, low progesterone in the second half of your cycle, and blood sugar instability that keeps cortisol spiking overnight. All of these produce fatigue that looks identical from the outside but has a very different underlying cause.

If you've had your thyroid tested and been told it's normal, it's worth knowing that standard thyroid panels often only test TSH, which is a pituitary hormone rather than a thyroid hormone itself. A full panel including T3, T4, and thyroid antibodies tells a much more complete story.

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Irregular, painful, or unpredictable periods

Your menstrual cycle is one of the most sensitive indicators of your overall hormonal health. When something is off, your cycle often shows it first.

Cycles that are shorter than 21 days, longer than 35, or that vary significantly month to month can point to disrupted ovulation, which affects progesterone production. Painful periods that require strong painkillers, or that produce large clots, are associated with elevated prostaglandins and conditions like endometriosis and adenomyosis. Absent periods in women who aren't pregnant or in menopause are a significant signal that the body has deprioritised reproduction in response to stress, low body weight, or over-exercise.

None of these are normal. Common, yes. Normal, no.

PMS that disrupts your life

Some degree of premenstrual awareness is physiologically normal. Your hormones are shifting and your body notices. What isn't normal is PMS that makes the week before your period feel unmanageable.

Mood instability, rage, crying without obvious cause, anxiety that spikes in the second half of your cycle, breast tenderness, bloating, cravings, and exhaustion that arrives like clockwork before your period. These are signs that the luteal phase hormonal shift is hitting harder than it should.

As I wrote about in Why Do I Feel Terrible in the Week Before My Period, the luteal phase is where the most can be done nutritionally. It is also where most women have been told the least.

Bloating and digestive symptoms

Persistent bloating, constipation, diarrhoea, and digestive discomfort that doesn't resolve despite dietary changes are frequently hormonal in origin, even when they look like purely digestive symptoms.

The gut and the hormonal system are in constant communication. Progesterone slows gut motility in the luteal phase, which is why many women notice bloating and constipation worsening before their period. The estrobolome, the collection of gut bacteria responsible for oestrogen metabolism, directly affects how much oestrogen circulates in your body. And cortisol, elevated under chronic stress, increases intestinal permeability and alters the gut microbiome in ways that produce digestive symptoms.

If your gut symptoms follow a cyclical pattern or worsen under stress, they are almost certainly connected to what's happening hormonally.

Hormonal acne

Breakouts along the jawline, chin, and lower cheeks that worsen in the second half of your cycle are a classic sign of androgenic activity and, often, insulin resistance.

Androgens, including testosterone and DHEA, stimulate oil production in the skin and can trigger inflammatory acne when elevated. Insulin resistance amplifies androgenic activity, which is one of the reasons PCOS so frequently presents with acne alongside irregular periods and weight changes.

Hormonal acne is not a skincare problem. Treating it exclusively with topical products, without addressing what's happening hormonally, is addressing the symptom rather than the cause.

Weight changes that don't respond to diet and exercise

Unexplained weight gain, difficulty losing weight despite genuine effort, or weight that redistributes to the abdomen and hips without obvious dietary cause are common hormonal symptoms that are chronically underserved by mainstream health advice.

Thyroid underfunction slows metabolism. Cortisol dysregulation promotes fat storage, particularly around the abdomen. Insulin resistance makes weight loss significantly harder regardless of calorie intake. And the standard advice, eat less and move more, addresses none of these.

If you do everything right and nothing changes, the answer is not to try harder. It's to look at what's actually driving the resistance.

Brain fog and poor concentration

Difficulty concentrating, poor short-term memory, the feeling of operating behind a layer of glass. These are symptoms that women frequently attribute to stress or age but that have clear hormonal drivers.

Oestrogen supports cognitive function, memory, and mood regulation. When oestrogen fluctuates significantly, as it does in the luteal phase and in perimenopause, cognitive symptoms often follow. Low thyroid function produces brain fog that can be significant. And chronically elevated cortisol impairs the part of the brain responsible for focus, decision-making, and working memory.

Brain fog is not a personality trait. It is a physiological response to something specific.

Low mood and anxiety

Mood is deeply hormonal, and this is something women are not told nearly enough.

Oestrogen supports serotonin production. Progesterone has a calming effect on the nervous system via its conversion to a neurosteroid called allopregnanolone, which acts on the same receptors as anti-anxiety medication. When progesterone is low, that calming effect is reduced, which is why anxiety often spikes in the luteal phase before a period.

This is not the same as a mental health condition, although it can look identical from the outside and the two can absolutely coexist. If your mood follows a clear cyclical pattern, worse in the second half of your cycle and better in the first, that's hormonal information worth taking seriously.

Low libido

A significant reduction in interest in sex is one of the most commonly experienced and least commonly discussed hormonal symptoms.

Testosterone, often thought of as exclusively male, plays an important role in female libido, energy, and motivation. Low testosterone, low oestrogen, and high cortisol all suppress libido. Hormonal contraceptives, particularly the combined oral contraceptive pill, can reduce testosterone levels and lower libido in some women. If you've noticed this since starting the pill, it is a recognised physiological response, not a psychological one.

What to do if you recognise yourself here

The first thing to say is that recognising several of these symptoms doesn't mean something is catastrophically wrong. It means your body is communicating something that deserves proper attention rather than being managed symptom by symptom.

The second thing to say is that these symptoms are not separate problems requiring separate solutions. They are almost always connected. Expressions of the same underlying picture viewed from different angles. Addressing that picture properly requires looking at the whole thing: your hormonal patterns, your gut health, your nervous system, your nutrition, and your life.

That's exactly the work I do.

Want to understand what's driving your symptoms specifically? The Root Cause Review is where to start.

Josie de Vries

Josie de Vries is a Nutritional Therapist specialising in women's hormone health, gut health, and nervous system regulation. Based in West Sussex, working with women across the UK and internationally.

https://josiedevries.com
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